Research Resource Core Laboratory

About the BIO Center

Our Services - Your Research

The BIO Center supports approximately 30 to 40 preformulation projects in a 12 month period.  This often involves the identification of solubility and stability issues and developing aqueous based formulations suitable for the use in maximum tolerated dose and pharmacokinetic studies in mice or rats.  As we progress into the formulation studies, we start with excipient compatibility studies and the generation of early prototype formulations.  We have stability chambers that our compliant with ICH requirements plus more accelerated storage at 50⁰C and 60⁰C to test early compatibility variants. 

The BIO Center provides services for internal and external academic investigators and commercial customers to establish and facilitate collaborations and to expand the scope of services the BIO Center can support.

  • Physical / chemical characterization of drug candidates
  • Compound solubilization
  • Stability evaluation and enhancement
  • Analytical and bioanalytical method development
  • Animal pharmacokinetic studies, early stage pharmacology testing
  • Formulation of dosing vehicles for animal studies
  • Develop new and novel dosage forms for application in human clinical studies, i.e. pediatric dosage forms

Drug Development Specializations

  • Preformulation and formulation
  • Analytical chemistry
  • Bioanalytical chemistry
  • Pharmacokinetics and pharmacology

The BIO Center has approximately 5,000 sq. ft. composed of 7 laboratory areas and associated office space on two floors of McCollum Laboratories and in the Higuchi Laboratories animal facility on West Campus.  A map showing our location is on the Contact page.

Contact the BIO Center

Michael J. Hageman, PhD

Lanaea Heine

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